Observations on a Strain of Spirochæta Pallida Isolated from the Nervous System

Spirochæta Pallida (Spironema Pallidum) in Syphilis

Spirochæta (treponema) Pallida and Syphilis

The extensive bibliography on experimental syphilis and spiroch~eta pallida has been brought together and reviewed recently by Hoffmann, 1 Neisser, 2 R. Kraus, 3 Glass, 4 and Buschke and Fischer, 5 in whose publications the present state of our knowledge on these subjects can be readily found. The weight of opinion is strongly in favor of accepting the transmissibility of the syphilitic virus t...

Concerning the Morphology and Reproduction of Spirochæta Pallida and a Rapid Method for Staining the Organism

The object of this paper is to describe a simple method for the staining in smear preparations of Spiroch~eta pallida and to present certain observations which I have been enabled to make upon the morphology and reproduction of the microorganism through the use of this staining method. I have examined a large number of cases of syphilis and various syphi-litic lesions, and it is upon the study ...

HYPERVITAMINOSIS A-INDUCED CENTRAL NERVOUS SYSTEM DEFECTS

In this investigation the effects of excess vitamin A administration during the early embryonic period were studied. Intramuscular injection of a single dose of 15000,20000 or 25000 IU/kg vitamin A to pregnant Balb/c strain mice on either day 7,8,9 or 10 of gestation (vaginal plug= day 0 of gestation) produced major malformations in the central nervous system (CNS) including exencephaly, h...

A Study of Complement Fixation in Syphilis with Spirochæta Culture Antigens

It is our purpose in this communication to give the results of some work upon complement fixation in syphilitic and other sera, using specific antigens prepared from pure cultures of Spirochceta pallida, Spirochceta pertenuis, and Spirochceta microdentia. The results are compared with those obtained with the same sera and a stock antigen used in our routine Wassermann tests, this antigen consis...